The four stars of the film, Colin Farrell, Brendan Gleeson, Barry Keoghan and Kerry Condon, have all been recognised for their individual performances.
Martin McDonagh’s dark Irish comedy sees the sudden end of a relationship between two life-long friends Padraic Suilleabhain and Colm Doherty, played by Farrell and Gleeson.
Keoghan plays the innocent, yet dim-witted Dominic Kearney while Condon takes the role of Padraic’s sister Siobhan.
Farrell is named in the top acting category – outstanding performance by a male actor in a leading role – after previously triumphing at the Golden Globes and earning a coveted Oscar nod in the equivalent categories.
Gleeson and Keoghan go head-to-head for outstanding performance by a male actor in a supporting role, while Condon is nominated in the female category.
Keoghan and Condon recently took home awards in the equivalent Bafta categories, though Gleeson is yet to scoop any awards this season.
The Banshees Of Inisherin also gained a nomination for best cast in a motion picture – the SAG equivalent of best picture – along with The Fabelmans, Babylon, Everything Everywhere All At Once and Women Talking.
Other contenders competing with Farrell in the outstanding actor in a leading role category include Bill Nighy, Adam Sandler, Brendan Fraser and Austin Butler.
Butler, who is also Oscar-nominated for his turn as Elvis Presley in Baz Luhrmann’s biopic, beat the Irish actor last week to claim Bafta’s best actor award.
In the category for SAG outstanding performance by a female actor in a leading role, Oscar-nominees Cate Blanchett, Michelle Yeoh and Ana de Armas received nods, as did Viola Davis and Danielle Deadwyler.
On the small screen British names have received fewer SAG nominations, though royal drama The Crown is recognised in the category for outstanding performance by an ensemble in a television drama series.
It takes on popular US series including HBO’s The White Lotus, Severance, Ozark, and Better Call Saul for the award.
Taron Egerton and Emily Blunt are nominated for outstanding performance by a male and female actor in a television movie or mini-series, respectively.
The 29th annual ceremony, which begins at 1am UK time, is taking place at the Fairmont Century Plaza in Los Angeles.