Vanessa Gillies claims the problem at the Glasgow G1-5 Delivery Office, located on Baird Street, have been going on for around two years.
She says the issue started after their regular postie was moved to another route.
Vanessa told the Glasgow Times: “We don’t get daily or weekly deliveries; it’s now down to once a fortnight. It’s unacceptable.
“I missed a really important letter about a hospital appointment because it never arrived and they e-mailed me and said ‘you’ve missed it’ but I never got the letter.
“Over the two years, there’s been quite a few I’ve missed. Earlier this year they sent out three letters and not one did I get.
“Any hospital letters I need to say to them now ‘phone me, don’t send me a letter, I won’t get it’.”
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Vanessa says due to issues with parcels not arriving she no longer orders online from places that use Royal Mail for deliveries.
The 52-year-old said: “There are several parcels I didn’t get last year because they were delivered through Royal Mail, but they just don’t care.
“Last year, I ordered four or five books for Christmas, and I just never got them.
“They told me I could complain to get the money back from the supplier but the point is, where are they?
“Not one of then has arrived even a year later.”
Vanessa, who says her neighbours are experiencing the same issues, has also received letters that are not for her.
She has complained twice to the Postal Review Panel but says she didn’t find them “very helpful”.
A response sent last October, seen by the Glasgow Times, said there has been “significant disruption” at the delivery office due to “acute staffing problems” but said there was an “ongoing plan in place” for daily deliveries to resume.
However, Vanessa says there has been no improvement since then.
She said: “The response has been diabolical.
“You go through all the rigmarole and they just give you a generic response.
“Nothing at all has changed.”
She continued: “How many times do people need to say we’re not getting out mail before they actually pay attention and sit up and say ‘something’s not right here’.
“They cover a massive area so what the hell is going on in that sorting office?”
The Glasgow Times previously reported in April that residents living in Garnethill, which is covered by the same delivery office, said there had been an ongoing issue with deliveries with letters for hospital appointments, jury duty, bank statements and fines among those not delivered in a timely manner.
Meanwhile, a resident living in Woodlands who is battling cancer and kidney disease also missed an appointment due to a letter failing to arrive.
In that same month, Alyson McKell, chair of Townhead and Ladywell Community Council, said residents in the area had been receiving Christmas cards four months late due to delays, and that residents were choosing to travel to the G1-G5 Delivery Office to pick up their letters.
Royal Mail has been contacted for comment.